Additional Info: Test includes N-Telopeptide and creatinine.
Useful For: NTx is useful to assess bone resorption in patients with metabolic bone disease and to monitor therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.
Methodology: Enhanced Chemiluminescence
Specimen Requirements:
Preferred:
USE SECOND MORNING VOID ONLY, 2 mL urine from second morning void (minimum volume 1.0 ml), refrigerated. DO NOT COLLECT FIRST AM VOID.
Acceptable:
Unpreserved random urine, unpreserved catheterized urine, or unpreserved first void clean catch urine.
NOTE: See “Urine Collection” located in “Specimen Collection & Preparation” section for timed collection instructions. Also refer to “Patient Information” section in back of manual for patient handout explaining collection information for this test.
Days Set Up: Monday through Saturday
CPT Information:
82523 – Collagen cross links, any method
82570 – Creatinine; other source